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Prostate growth is caused by a hormone in the blood called dihydrotestosterone (DHT). AVODART lowers DHT production in the body, leading to shrinkage of the enlarged prostate in most men. Just as your prostate became large over a long period of time, reducing the size of your prostate and improving your symptoms may take time.

Generic Avodart reduces urinary blockage and improves urine flow. This medicine should not be used in women and children.

While dutasteride is officially approved to treat enlargement of the prostate gland, it may also be used to treat male pattern baldness. But clinical trials for dutasteride as a hair loss drug were called off in late 2002. The reason the trials were called off is not publicly known. Industry sources speculate that Avodart would have been seen as too similar to Propecia to have proved profitable as a hair loss treatment.

Dutasteride (Avodart) inhibits both type I and type II, 5?-Reductase. At the 0.5-Mg dose it is about 3 times as potent as finasteride at inhibiting type II, 5?-Reductase enzyme and more than 100 times as potent at inhibiting the type I 5?-Reductase enzyme. Type I receptors inhibited by dutasteride are present in other organs of the body besides the skin, including the liver and kidneys.

The maximum effect of Avodart can be observed within 1 to 2 weeks. After 1 and 2 weeks of daily dosing with Avodart 0.5Mg, median serum DHT concentrations were reduced by 85% and 90% respectively.

Marrylifang(At)hotmail(Dot)comName: China Dutasteride powderTrade name: AvodartDutasteride Assy: Purity 98.5% Molecular Formula: C27H30F6N2O2Molecular Weight: 528.5 CAS Number: 164656-23-9Packing: As your requireAppearance: White to pale yellow powder.

Avodart can be given as monotherapy or in combination with ?-Receptor blocker tamsulosin (0.4 Mg). Adult males (Including the elderly) the recommended dose of Avodart - 1 capsule (0.5 Mg) per day by mouth. Capsule swallowed whole, do not open and do not chew, because when in contact with the contents of the capsule may irritation of oral mucosa and pharynx. Avodart can be taken regardless of meals. Despite the fact that the decrease in severity of symptoms can celebrate after a short time after taking the drug for an objective assessment of the effectiveness of drug treatment should be continued for at least 6 months. Renal failure for patients with renal insufficiency to adjust the dose is not necessary.

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Dutasteride (Avodart) is a potent inhibitor of both Type I and Type II isoenzymes of 5 alpha-reductase. Dutasteride was approved for the treatment of benign prostatic hyperplasia in 2002 by the FDA but does not have an indication for hair loss. At a 0.5 Mg daily dosage, dutasteride reduces dihydrotestosterone (DHT) levels by over 90% as compared with finasteride, which reduces DHT by 70% at a 1 mg daily dose. As Type I 5 alpha-reductase accounts for approximately 30% of circulating DHT, dutasteride blocks the Type I isoenzyme by 60% better than finasteride.

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